Mmanụ ylang-ylang

Aha ya bụ Ylang-ylangmmanụ dị mkpa (YEO), nke sitere na okooko osisi nke osisi okpomọkụCanangaodoratanko. f. & Thomson (ezinụlọAnnonaceae), ejirila ya mee ihe na ọgwụ ọdịnala nwere ọtụtụ ojiji, gụnyere nchekasị na ọnọdụ neuronal gbanwere. Mgbu Neuropathic bụ ọnọdụ mgbu na-adịghị ala ala nke nwere nnukwu ihe na-akpata ọrịa, dị ka nchekasị, ịda mbà n'obi, na nsogbu ọnọdụ uche ndị ọzọ, nke na-emetụta ndụ onye ọrịa nke ukwuu. Ọgwụ ndị dị ugbu a na-eji maka nchịkwa nke nhụjuanya neuropathic ezughị oke n'ihi adịghị arụ ọrụ na-adịghị mma na ndidi, na-egosipụta mkpa ọgwụ nke ọgwụgwọ ọgwụ ka mma. Ọtụtụ nchọpụta ụlọ ọgwụ ekwuola na ịhịa aka n'ahụ ma ọ bụ iku ume na mmanụ ndị dị mkpa ahọpụtara na-ebelata mgbaàmà metụtara mgbu na nchekasị.

Ebumnobi ọmụmụ a bụ iji nyochaa mmetụta analgesic nkeYEOyana ịdị irè ya n'ibelata mgbanwe ọnọdụ ọnọdụ metụtara neuropathy.

A nwalere ihe mgbakasị ahụ n'ụdị mmerụ ahụ echekwabara site na iji ụmụ oke nwoke. A tụlekwara akụrụngwa anxiolytic, antidepressant na locomotor site na iji ule omume. N'ikpeazụ, a nyochara usoro ọrụ YEO na ọkpụkpụ azụ na hippocampus nke ụmụ oke neuropathic.

nchịkwa ọnụ nkeYEO(30 mg / kg) belatara ihe mgbu neuropathic nke SNI na-ebute ma na-eme ka mgbaàmà nchegbu metụtara mgbu pụta ìhè ụbọchị 28 mgbe ịwachara ahụ.YEObelata okwu nke MAPKs, NOS2, p-p65, akara nke neuroinflammation, ma kwalite mmetụta normalize na ọkwa neurotrophin.

YEOkpalitere ihe mgbu neuropathic mgbu na nchekasị na-emetụta mgbu na-eme ka ọ dịkwuo mma, na-anọchite anya onye na-adọrọ mmasị maka nlekọta nke ọnọdụ nhụjuanya neuropathic na ihe mgbu metụtara ihe mgbu.