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Dị ọcha eke organic magnolia mkpa mmanụ flos magnoliae mmanụ maka senti mmanụ

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Magnoliae Flos bụ ọgwụ ọdịnala a na-ejikarị eme ihe na Eshia. A na-eji ya agwọ Sinusitis, imi imi, na anụ ahụ na-adịghị ahụkebe. N’ihi na a kọwara Magonlia Flos dị ka ihe na-esi ísì ụtọ n’ihe odide ndị China oge ochie, anyị chere na a pụrụ iji mmanụ ya dị mkpa gwọọ ọrịa ndị na-alụso ọrịa ọgụ. Mkpụrụ ndụ Dendritic (DCs), ndị a na-ewere dị ka isi ebumnuche nke immunomodulators iji chịkwaa nzaghachi mgbochi ọrịa, na-arụ ọrụ dị oke mkpa na nzaghachi mgbochi mgbochi. N'ime ọmụmụ ihe a, Magnoliae Flos mmanụ dị mkpa (MFEO) belatara mmepụta nke cytokines TNF-α, IL-6, na IL-12p70 na lipopolysaccharide (LPS) -kpaliri DCs. Ọ kpachiri akara nrịbama elu MHC II, CD80, na CD86 n'ime DC-akpalite LPS. Ụdị anụmanụ gosipụtara na 2,4-Dinitro-1-fluorobenzene (DNFB) na-ebute nzaghachi hypersensitivity kọntaktị na-egbochi ọgwụgwọ na MFEO. Na mgbakwunye, MFEO gbochiri ntinye nke mkpụrụ ndụ T na ntị nke ụmụ oke ndị DNFB kpatara. Iji nyochaa ogige bioactive ya, a na-enyocha akụkụ nke MFEO site na iji gas chromatography (GC) na GC-mass spectrometry. Nsonaazụ gosiri na isi ogige dị na MFEO bụ camphor na 1,8-cineole. Mgbakwunye bioassay nke DC kwadoro na ogige ndị a kwụsịrị mmepụta cytokine nke ukwuu na DC nke LPS kpatara. Ya mere, anyị gosipụtara na MFEO na-egosipụta mmetụta immunosuppressive ma na vivo na in vitro, na camphor na 1,8-cineole nwere ike ịbụ ihe ndị bụ isi na-ahụ maka ikike immunosuppressive ya. Ihe nchoputa a gosiputara na MFEO nwere ike imeputa dika ihe mgbochi ohuru maka oria buru ibu.


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    Magnoliae Flos bụ ọgwụ ọdịnala a na-ejikarị eme ihe na Eshia. A na-eji ya agwọ Sinusitis, imi imi, na anụ ahụ na-adịghị ahụkebe. N’ihi na a kọwara Magonlia Flos dị ka ihe na-esi ísì ụtọ n’ihe odide ndị China oge ochie, anyị chere na a pụrụ iji mmanụ ya dị mkpa gwọọ ọrịa ndị na-alụso ọrịa ọgụ. Mkpụrụ ndụ Dendritic (DCs), ndị a na-ewere dị ka isi ebumnuche nke immunomodulators iji chịkwaa nzaghachi mgbochi ọrịa, na-arụ ọrụ dị oke mkpa na nzaghachi mgbochi mgbochi. N'ime ọmụmụ ihe a, Magnoliae Flos mmanụ dị mkpa (MFEO) belatara mmepụta nke cytokines TNF-α" ọrụ =" ngosi" ụdị =" igbe-sizing: oke-igbe; ngosi: inline; ahịrị-ịdị elu: nkịtị; oghere okwu: nkịtị; ngabiga-eke: nkịtị; oghere ọcha: nowrap; sere n'elu: ọ dịghị; uzo: ltr; nnukwu obosara: enweghị; max-elu: ọ dịghị; obosara nkeji: 0px; min-elu: 0px; oke: 0px; ihe mgbochi: 0px; oke: 0px; ọnọdụ: ikwu;”>α

    , IL-6, na IL-12p70 na lipopolysaccharide (LPS) -kpaliri DC. Ọ kpachiri akara nrịbama elu MHC II, CD80, na CD86 n'ime DC-akpalite LPS. Ụdị anụmanụ gosipụtara na 2,4-Dinitro-1-fluorobenzene (DNFB) na-ebute nzaghachi hypersensitivity kọntaktị na-egbochi ọgwụgwọ na MFEO. Na mgbakwunye, MFEO gbochiri ntinye nke mkpụrụ ndụ T na ntị nke ụmụ oke ndị DNFB kpatara. Iji nyochaa ogige bioactive ya, a na-enyocha akụkụ nke MFEO site na iji gas chromatography (GC) na GC-mass spectrometry. Nsonaazụ gosiri na isi ogige dị na MFEO bụ camphor na 1,8-cineole. Mgbakwunye bioassay nke DC kwadoro na ogige ndị a kwụsịrị mmepụta cytokine nke ukwuu na DC nke LPS kpatara. Ya mere, anyị gosipụtara na MFEO na-egosipụta mmetụta immunosuppressive abụọna vivonana vitro, na camphor na 1,8-cineole nwere ike ịbụ ihe ndị bụ isi na-ahụ maka ikike mgbochi ya. Ihe nchoputa a gosiputara na MFEO nwere ike imeputa dika ihe mgbochi ohuru maka oria buru ibu.








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