Viticis Negundo Foium dị ọcha maka kandụl na ncha na-eme nnukwu mgbasa ozi dị mkpa mmanụ ọhụrụ maka ndị na-ere ọkụ ahịhịa amị.

Mpaghara nka

Ihe mepụtara ugbu a metụtara ubi mmanụ na-agbanwe agbanwe nke osisi dị ọcha nwere akwụkwọ ise, bụ ụdị nkwadebe nke mmanụ na-agbanwe agbanwe nke osisi dị ọcha nwere akwụkwọ ise.

Nkà na ụzụ ndabere

Na nri ụlọ ọrụ, sanitas bụ otu n'ime ihe ndị kasị mkpa mgbakwunye.Ọ bụ na a na klas ga-na-nri nri mmako na-echebe nri uru na mbụ agwa bụ object.Ut now ot sanitas bụ na ọtụtụ na chemosynthesis sanitas na ụwa, ma na-arapara nke. chemosynthesis sanitas bụ carcinous, teratogenecity na nsogbu ndị dị ka nri na-adịghị ala ala nsị nke na-akpata n'ụzọ dị mfe na-akpata nchegbu ọha na eze. mgbanwe ntụziaka dị ka " elu "na" eke ". Ya mere, nnyocha na mmepe nke eke ọtọ nri nri sanitas dị nnọọ iyi ihe ọzọ na ndị ọzọ mkpa.Antiseptics maka eke nri nwere ike kewara n'ime microbialpreservatives (N,O-Diacetylmuramidase, nisin, tennecetin, epsilon-polylysine), creatural preservative (protamine, propolis, chitosan) na osisi isi iyi antiseptik gị n'ụlọnga (tii-polyphenol, osisi mkpa mmanụ, garlicin, anthraquinone herbal ọgwụ) .Osisi mkpa mmanụ bụ ebe klas eke vegetal nri mgbakwunye, nwere ike. ziri ezi nri peculiar isi, nye senti, na-ese, mgbochi oxidant, ọgwụ nje (anticorrosion) na physiological na pharmacological mmetụta na mgbakwunye na nwere. Dị ka otu n'ime ihe ndị dị mkpa na isi mmalite nke eke antiseptik gị n'ụlọnga, si osisi mkpa mmanụ, iyo si arụ ọrụ nke ọma, akụ na ụba. ihe nchekwa nchekwa dị ka ihe nchekwa nri, nwere atụmanya ngwa sara mbara yana mkpa nyocha nke ukwuu.

Ka ọ dị ugbu a, nchọpụta nje na-akụ ihe dị ukwuu, dị ka nsonaazụ nyocha ya si dị, enwere ike kewaa ya n'ụzọ atọ dị iche iche: iji mee ka mmetụta mgbochi ahụ nyocha nke nje bacteria na-emebi nri na-achọpụta ihe nchekwa nri eke, igbochi mmetụta nyocha nke phytopathogen bụ. mepụtara n'oge a na mgbochi mmetụta nnyocha nke mmadụ ahụ pathogenic nje bacteria na-emepụta na newtype drug.Ka ọ dị ugbu a, dị ka e kewara ọzọ saịtị nke edinam nke osisi nnyocha: wepụ osisi mkpa mmanụ na-ebu antibacterial nnyocha, mgbọrọgwụ osisi, azuokokoosisi, akwukwo. A na-eme nnwale nke nje bacteria na nyocha ọrụ mgbochi microbial iji mepụta mkpụrụ osisi endogenesis na mmịpụta ihe mgbaze organic.

N'ihi na ihe a na-emepụta ugbu a bụ ka e bu n'obi ka osisi dị ọcha nke nwere akwụkwọ ise na-amịpụta mmanụ; a ga-etinye ya na lotus rhizome mgbochi corrosive idobe ọhụrụ; ihe onwunwe biocidal, nchekwa dị ka ihe nchekwa nri sitere na osisi; inweta akwụkwọ ndụ akwụkwọ ndụ, nchekwa na ntụkwasị obi nke sitere n'osisi ihe nchekwa nri; maka mmepe zuru oke na itinye n'ọrụ nke osisi dị ọcha nwere akwụkwọ ise na-enye ndabere nnwale; melite itinye n'ọrụ ruru nke osisi akụ, ike elu aku na uba uru.

Osisi dị ọcha nke nwere akwụkwọ ise (Vitex negundo Linn) bụ ụdị Verbenaceae Vitex, aha ọzọ osisi mmanya dị ọcha nke nwere akwụkwọ ise, Fructus Viticis Negundo, osisi dị ọcha akwa, alaka nke osisi dị ọcha, ifufe mkpịsị aka ise, Folium vilicis Negundo. kwa afọ machaka ma ọ bụ dungarunga, na osisi elu nwere ike iru 6m, na alaka, akwukwo na azuokokoosisi niile na-esi ísì ụtọ, si base portion alaka ụlọ ọrụ, na nso raw canescence mma ntutu. Akwụkwọ bụ ndụ, na palmately compound akwukwo, nwere ogologo aka, mpempe akwụkwọ 3. -5 mpempe akwụkwọ, na ìhè akwụkwọ ndụ akwụkwọ ndụ, bụ elliptical avette ka lanceolar, zuru onu ma ọ bụ ubé sawtooth, na-acha ọcha ntutu dị mma nke nso ndụ na azụ n'akụkụ, rubbing nwere peat-reek.The kwesịrị ekwesị ịdị adị nke ise-leaved dị ọcha osisi n'ime. torrid zone na Temperate Region na China, na-ekesa n'ọtụtụ ebe na China Yangtze Valley na mpaghara ọ bụla na mpaghara, n'ebe ndịda, nakwa na e nwere nkesa na Shandong.Eastern Africa na-ekesa nke ukwuu site n'ala dị ka Bolivia nke Madagascar, ndịda ọwụwa anyanwụ, Asia na. South America.

Mkpụrụ vitex na-acha odo odo, akwụkwọ, alaka na mgbọrọgwụ niile enwere ike iji dị ka ọgwụ. Mkpụrụ vitex na-acha odo odo nwere apophlegmatic na-ebelata ụkwara ma na-ebelata mmetụta nke bronchospasm, na-agwọkwa ọrịa karịsịa flu, ụkwara, ụkwara ume ọkụ, ọrịa ogbu na nkwonkwo, ịba, afo mgbu, hernia, gbasara fistula. etc.Negundo Chastetree akwukwo nwere ike na-ebelata superficies site jụrụ, iwepu keguru mmiri, detoxifying, na-agwọ tumadi flu, heatstroke, vomiting na afọ ọsịsa, ọnyụnyụ ọbara, ịba, jaundice, rheumatism, na-emeso ọzịza na mgbu site traumatic mmerụ ahụ, mgbu mange, na nwere ike igbochi ndị ahụ. mmepe nke formaldehyde sacroiliitis mbufụt. The decoction nke Negundo Chastetree Akwụkwọ ma ọ bụ mgbọrọgwụ nwere mgbochi mmetụta na bacillus dị ka streptococcus aureus, beta hemolytic streptococcus na nnukwu eriri afọ, anthrax, diphtheria, typhoid fever, green pus, ọnyụnyụ ọbara.

Ise-leaved dị ọcha osisi osisi mkpa mmanụ, na-azọrọ senti mmanụ ma ọ bụ obodo mmanụ, bụ klas osisi-sourced secondary metabolism klas ihe, bụ molekụla arọ na osisi ihe, ike steams na mmiri vapour, nwere volatility mmanu mmanu mmiri umi nke ụfọdụ isi isi. .Essential mmanụ bụ n'ozuzu wepụ mkpụrụ osisi, ifuru, akwukwo na mgbọrọgwụ si osisi, nwere ike na-esi ísì ụtọ ma ọ bụ ísì.The chemical mejupụtara ọzọ mgbagwoju anya na ọ dị, nwere ike kewara n'ime aliphatics, aromatic usoro na terpene atọ isi ụdị na ha nwere. oxygen derivative dị ka mmanya, aldehyde, ketone, acid, ether, ester, lactone wdg site chemical Ọdịdị, nwekwara na mgbakwunye na nitrogenous na compound sọlfọ-bearing.Conventionally osisi mkpa mmanụ na-eji na-akwadebe essence na ekpomeekpo gị n'ụlọnga, ma na ikpeazụ. afọ ole na ole, mgbochi microbial ọrụ nke osisi mkpa mmanụ na otu akụkụ ya e rụrụ na a nnukwu ego nke nnyocha ma n'ụlọ na ná mba ọzọ.Research na-egosi, na osisi mkpa mmanụ nwere bụ antibacterial, desinsection, mgbochi oxidant isoreactivity, n'akụkụ dịka ọgwụ, kemịkalụ ugbo, ihe mgbakwunye nri nri, ejirila ya mee ihe.

Osisi na-adịghị mma nke nwere akwụkwọ ise nwere nnukwu ọrụ ụmụ ahụhụ na-eme ka ụmụ ahụhụ ndị na-echekwa ọka dị ka sitophilus zea-mais, Callosobruchus chinensis, ndị na-eri ọka dị obere, ma nwee ike ịchịkwa Fl nke ọma maka ịmepụta ọnụ ọgụgụ mmadụ, na-ebelata ọnụọgụ ya.Monomer Terpane, firpene. Ha niile nwere ọrụ ụmụ ahụhụ dị elu na corundum Sitophilusspp. imago, bụ ụmụ ahụhụ nọ n'ọrụ bekee dị mkpa na ise-leaved dị ọcha osisi mgbanwe mmanụ.The employing uzuoku distillations dị ka Yang Haixia wepụ agbanwe agbanwe mmanụ si ise-leaved dị ọcha osisi.Utilize gas chromatography/mass spectrometry technology (GC.MS) iji mụọ kemikal. mejupụtara ise-leaved dị ọcha osisi obodo mmanụ.Be kewapụrụ kpam kpam 37 ogige, chọpụtara ebe 28.Mainly mejupụtara caryophyllene (23.981%) .Huang Qiong (2008) wdg wepụ obodo mmanụ nke Vitex negundo var cannabifolia na ngwa ndakwa nri irradiation, jiri ngwa ndakwa nri irradiation. capillary gas chromatography otu MS na njikọ na kọmputa search, ya chemical mejupụtara na-rụrụ karị ka analysis na njirimara, site na mpaghara normalization usoro, tụọ ikwu ọdịnaya nke ọ bụla compound na obodo oil.Result achọpụta 16 ogige kpam kpam, na volatilization isi ahu nke. mmanụ bụ caryophyllene (20.14%).

Wepụ ihe ndị ọzọ ot amịpụta usoro nke osisi na-agbanwe agbanwe mmanụ na nwere uzuoku distillation (mmiri distillation usoro, distilling n'elu mmiri usoro, uzuoku distillation), mmiri mgbasa usoro, ihe mgbaze mmịpụta usoro, absorption usoro, supercritical CO₂abstraction Usoro, ultrasonic ife inyeaka mmịpụta technology, ngwa ndakwa nri radieshon induction abstraction Usoro, enzyme mmịpụta technology etc.Shortcoming bụ ibibi nnukwu ka okpomọkụ na-enwe mmetụta nke ihe na-ejighị n'aka mejupụtara.

Nchịkọta nke mepụtara

Ihe nke mepụtara bụ inye ụdị n'ọrụ imekotaotuugbo distillation usoro, na-eji nkwadebe usoro megide polarity organic mgbaze mmịpụta ise-leaved dị ọcha osisi agbanwe agbanwe mmanụ.

Atụmatụ nka nke ihe a rụpụtara ugbu a bụ, e ji mara ya na ịnakwere ma tụọ 10g ntụ ntụ dị ọcha akwụkwọ ndụ akwụkwọ ndụ ise n'ime flask gbara gburugburu nke 1000ml, gbakwunye mmiri distilled 300mL ma mee ka mmiri dị ukwuu, nweta 50mL hexane nkịtị na flask 500ml. , jikọọ distilling na wepụ ngwaọrụ n'out oge, mee ka ihe otu ọgwụgwụ na-na banyere 110 ± 5 ℃ nke nta esi ọnọdụ okpomọkụ, organic mgbaze-nkịtị hexane otu ọgwụgwụ okpomọkụ na-achịkwa na 80 ℃ ± 5 ℃, na-emeso niile na reflux na abụọ amalite oge. ma na-ekwusi ike 4h, mgbe mmịpụta, organic reagent na-ebufe na ngwá ọrụ nkwụnye triangular flask, gbakwunye anhydrous sodium sulphate ịbụ ezi-grannular na-enweghị nnukwu caking, refrjiraeto n'otu ntabi anya, mgbe gafere millipore filtration nke 0.45 μm, rotary evaporation bụ residual on a. obere obere, nyefe na karama injection sample na nitrogen na-afụ ka isi ísì na-enweghị ihe mgbaze, nweta mmanụ na-agbanwe agbanwe, enwere peat-reek siri ike, a na-eme mmanụ a dị mkpa na nyocha GC-MS na ntanetị, organic reagent normal hexane gbanwere. na-eme hexanaphthene (90 ℃ ± 5 ℃ nke okpomọkụ), methylene dichloride (50 ℃ ± 5 ℃), ethyl acetate (90 ℃ ± 5 ℃) na-eji otu usoro na-ebu mgbe distillation mmịpụta, distillation mmịpụta bụ na sample aqueous. A na-etinye ihe ngwọta na reagent organic n'otu n'otu na akụkụ abụọ nke ngwá ọrụ ma na-ekpo ọkụ na-esi n'out oge, mmiri vapo na ihe mgbaze vapo(u) r n'ụzọ zuru ezu mix na ngwaọrụ, n'out oge condensation na-enweta oyi na organic ihe mgbaze akụrụngwa na aqueous frasi amịpụtara mgbe niile. ka na usoro unyi tinyere ogologo, n'ihi na mmiri na organic na-adọ na-adịghị etisasịwo onye ọ bụla ọzọ na U-ekara ọkpọkọ na-ekewa, na-aghachi n'otu n'otu na flask nke abụọ, site distillation, mmịpụta usoro na-aga n'ihu, mgbasa, iru na ihe nke ogige ndị na-adịghị agbanwe agbanwe na nke na-adịghị agbanwe agbanwe nke nchọta na mmịpụta, nkewa na mmepụta ihe.

N'ihi n'inwe usoro usoro a nakweere, usoro mmepụta ihe nke nyocha nwere njiri mpụta mmịpụta dị elu, dị mfe iji rụọ ọrụ; A na-eji ya maka nchekwa ọhụrụ nke lotus rhizome ọhụrụ, mmetụta dị mma; Nye aka iji kwalite ọdịnaya nke ogige ebumnuche.